Nickel Borate: A New Catalyst for Heterocycles Synthesis
Nagesh Sutar *
Department of Chemistry, Smt. Chandibai Himathmal Mansukhani College (Autonomous), Ulhasnagar-421003, Maharashtra, India.
*Author to whom correspondence should be addressed.
Abstract
The synthesis of 2,4,5-Triaryl-1H-imidazole derivatives is effectively accomplished via a facile and adaptable multicomponent reaction pathway. This process, catalysed by Nickel (II) borate in Acetone, involves the reaction of a 1,2-dicarbonyl compound, an aromatic aldehyde, and ammonium acetate, which functions as the in-situ ammonia source. This approach offers advantages which include simple workup, moderate to high reaction rate and satisfactory product yields.
Keywords: 2,4,5-Triaryl-1H-imidazole, multicomponent reaction, Nickel (II) borate, simple workup, satisfactory product yields