Bauhinia thonningii Schumach & Thonn (Fabaceae): Phytochemical Screening and Evaluation of the Antibacterial Activity of Barks
Bredou Jean Brice *
Laboratoire de Chimie Bio-Organique et de Substances Naturelles, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire.
Adou Demel Axel
Laboratoire de Chimie Bio-Organique et de Substances Naturelles, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire and Départment des Sciences et Techniques, Université Alassane Ouattara, 01 BP 18 Bouaké 01, Côte d’Ivoire.
Boua Boua Benson
Laboratoire de Chimie Bio-Organique et de Substances Naturelles, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire.
*Author to whom correspondence should be addressed.
Abstract
The aim of this study was to identify the groups of chemical compounds present in the aqueous extract of B. thoninginii bark from Ivorian flora and to assess its antibacterial activity against multi-resistant strains of P. aeruginosa and A. baumannii. Phytochemical sorting was used to identify polyphenols, flavonoids, tannins, coumarins, alkaloids, terpenes and derivatives. The levels of polyphenols, flavonoids, flavone aglycones, anthocyanins and condensed tannins were respectively 0.748 ± 0.03, 0.091 ± 0.01, 0.0094 ± 0.03, 0.0359 ± 0.01 and 0.117 ± 0.02 mg EAG /g MS. Sensitivity tests showed that BT was ineffective against multi-resistant strains of P. aeruginosa and A. baumannii.
Keywords: Bauhinia thonningii, Pseudomonas aeruginosa, Acinetobacter baumannii, aeruginosa and A. baumannii, antibiotics, conventional medicine, polyphenols