Assessment of Occupational Risks in the Toxicology and Pharmacology Laboratory Using the FMECA Method
Khalid Laarej
Research and Medical Analysis Laboratory of the Fraternelle of the Royal Gendarmerie, Rabat, Morocco.
Mohammed Jbilou
Research and Medical Analysis Laboratory of the Fraternelle of the Royal Gendarmerie, Rabat, Morocco.
Mustapha Bouatia
Laboratoiry of Analytical Chemistry and Bromatology, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, Morocco.
Adil Elyadini
Laboratory of Spectroscopy, Molecular Modeling, Materials, Nanomaterials, Water and Environment, Faculty of Sciences Rabat, Mohammed V. University, Rabat, Morocco.
Rachid Alami *
Research and Medical Analysis Laboratory of the Fraternelle of the Royal Gendarmerie, Rabat, Morocco.
*Author to whom correspondence should be addressed.
Abstract
The Toxicology and Pharmacology Laboratory is a high-risk work environment, especially the chemical risk that appears when people are exposed to reagents and chemicals. A corrective approach is required to identify and control these risks. The aim of this study is to determine how to manage the analytical risks at LTP designated for the dosage of drugs and poisons (narcotics, pesticides, mycotoxins, etc.). For this purpose, the risk analysis applying the FMECA method, a risk management tool that aims on the one hand, to qualitatively analyze the process, to analyze the failure modes, the causes and their effects, and to on the other hand, rate the criticality defined by the parameters of frequency of occurrence, severity and detection that will allow a quantitative analysis of each of the failure modes. Thus, the criticality calculation will help to determine the critical risks to be corrected, and to recommend corrective and preventive actions to be implemented within the service.
Keywords: Pharmacology, toxicology, FMECA method, analytical workstation phase