Phenolic Compounds of Rumex L: Aerial Part Fractions and Essential Oil Results of In vitro Screening for Antimicrobial Activity
G. D. Shermatova *
Institute of the Chemistry of Plant Substances named after Acad. S.Yu. Yunusov Academy of Sciences of the Republic of Uzbekistan, 100170, 77, M. Ulugbek str., Tashkent, Uzbekistan.
Kh. M. Bobakulov
Institute of the Chemistry of Plant Substances named after Acad. S.Yu. Yunusov Academy of Sciences of the Republic of Uzbekistan, 100170, 77, M. Ulugbek str., Tashkent, Uzbekistan.
B. A. Shamuratov
Institute of Bioorganic Chemistry named after Acad. O.S. Sadykov Academy of Sciences of the Republic of Uzbekistan, 100125, 83, M. Ulugbek str., Tashkent, Uzbekistan.
S. M. Mavlyanov
Institute of Bioorganic Chemistry named after Acad. O.S. Sadykov Academy of Sciences of the Republic of Uzbekistan, 100125, 83, M. Ulugbek str., Tashkent, Uzbekistan.
Y. J. Zhang
Kunming Institute of Botany, Chinese Academy of Sciences, 650201, 132, Lanhei Road, Heilongtan, Kunming, China.
K. A. Eshbakova
Institute of the Chemistry of Plant Substances named after Acad. S.Yu. Yunusov Academy of Sciences of the Republic of Uzbekistan, 100170, 77, M. Ulugbek str., Tashkent, Uzbekistan.
Sh. S. Azimova
Institute of the Chemistry of Plant Substances named after Acad. S.Yu. Yunusov Academy of Sciences of the Republic of Uzbekistan, 100170, 77, M. Ulugbek str., Tashkent, Uzbekistan.
S. A. Sasmakov
Institute of the Chemistry of Plant Substances named after Acad. S.Yu. Yunusov Academy of Sciences of the Republic of Uzbekistan, 100170, 77, M. Ulugbek str., Tashkent, Uzbekistan.
*Author to whom correspondence should be addressed.
Abstract
The aim of the present study to clarify the phytochemical constituents of Rumex plants, extraction, separation and structural identification of chemical components, provide theoretical support and scientific basis for its traditional use, further expand the application scope of traditional medicinal plant resources in Uzbekistan, and develop its potential value. Three known anthraquinone derivatives has been isolated from the chloroform fraction extract of Rumex pamiricus roots and two known compounds were separated from the ethyl acetate fraction extract of Rumex conglomeratus roots. Their structures were elucidated by extensive spectroscopic evidence and chemical methods. Qualitative analyses of major phenolics by TLC analysis were also evaluated. The ester oil from the aerial parts of Rumex confertus and Rumex pamiricus, the gasoline, chloroform, ethyl acetate and butanol extracts of Rumex pamiricus aerial part and alcohol extract of Rumex pamiricus roots were tested in vitro for antimicrobial activity.
This study aimed to determine the in vitro antimicrobial activity of the medicinal plants traditionally used in Uzbekistan against the microbial strains associated with infectious diseases.
Keywords: Polygonaceae L., Rumex pamiricus Rech. f., Rumex conglomeratus Murray, Rumex confertus Willd, sorrel, dock, phenol, phenolic acid, flavonoid, anthraquinone, In vitro, antimicrobial, extract, fraction