Assaying Antioxidant and Antimicrobial Activities of 1-phenyl-3-naphthoic acid Derivatives
R. P. Mahashabde *
Department of Chemistry, Institute of Science, Rabindranath Tagore Road, Civil Lines, Nagpur-440010, India
N. S. Kadam
Datta Meghe Institute of Engineering Technology & Research, Wardha-442001, India
S. S. Deo
Department of Chemistry, Institute of Science, Rabindranath Tagore Road, Civil Lines, Nagpur-440010, India
F. Inam
Department of Chemistry, Institute of Science, Rabindranath Tagore Road, Civil Lines, Nagpur-440010, India
*Author to whom correspondence should be addressed.
Abstract
Laboratory synthesized 1-phenyl naphthoic acid systems (substituted naphthalenes or lignans) were evaluated for their antioxidant and antimicrobial potential. All the phenyl naphthoic acids showed significant to moderate antioxidant activity in DPPH (2, 2-diphenyl- 1-picrylhydrazyl) and FeCl3 (ferric chloride) assay.
All the lignan compounds exhibited significant to moderate antimicrobial and antifungal activity except one of the compounds which showed no toxicity to the fungal species.
Keywords: 1-phenylnaphthoic acids, antioxidant potential, antimicrobial potential