Metabolites Detected in the Crude N-Hexane Extract of Artemisia annua Linn (Asteraceae) Cultivated in Langtang, Plateau State, Nigeria
Cyril E. Manulu
Department of Chemistry, Faculty of Natural Sciences, University of Jos, Jos, Plateau State, Nigeria
Esther A. Adelakun
Department of Chemistry, Faculty of Natural Sciences, University of Jos, Jos, Plateau State, Nigeria
Jeremiah I. Abok *
Department of Chemistry, Faculty of Sciences, Federal University Lafia, Nasarawa State, Nigeria
*Author to whom correspondence should be addressed.
Abstract
Artemisia annua was grown in and harvested from Langtang, Plateau State in Nigeria. The dried pulverized aerial part of Artemisia annua was extracted with n-hexane by percolation and concentrated in vaccum at 40°C. Analysis of crude n-hexane extract by GC-MS revealed twelve major compounds, which were mostly terpenoids. These are Deoxyqinghaosu (6.85%), Arteannuic acid (3.99%), Caryophyllene oxide (4.49%), 9-Octadecenoic acid (25.54%), Camphor (2.93%), Borneol (1.48%), 5,5Dimethyl-6-methylenebicyclo[2,2,1]hept-2-yl acetate (1.18%), 2,6-dimethyl-3,5,7-octatriene-2-ol, E,E (1.48%), Carveyl acetate (0.52%), Spathulenol (1.57%), α-Cubebene (0.66%), β-Farnesene (0.57%). The result suggests that the Artemisia annua chemotypes cultivated in Langtang area of Plateau State, Nigeria, may be related to those grown in Ethiopia.
Keywords: Artemisia annua L., metabolites, GC-MS, terpenoids